Serving Rockville & nearby areas • Most major insurances accepted

Esketamine (Spravato) for Treatment Resistant Depression in Adelphi, MD

FDA-approved esketamine therapy for adults with treatment-resistant depression—delivered under expert psychiatric supervision.

When depression hasn’t improved despite multiple medications, Spravato® (esketamine) may offer a clinically proven option. Treatment is administered in-clinic with careful monitoring and combined with an oral antidepressant as part of a structured care plan.

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Is Esketamine (Spravato) right for you?

FDA-Approved Treatment

Spravato® is FDA-approved for adults with treatment-resistant depression and used under strict clinical guidelines.

Non-Invasive Care

Spravato® is a nasal spray taken in-clinic—no surgery, no needles, and no anesthesia required.

Covered by Most Insurance Plans

Many major insurance plans cover Spravato®. Our team helps verify benefits and manages the approval process for you.

Minimal Downtime

Treatment sessions include a short observation period. Most patients return home the same day, though you’ll need a ride after your visit.

Covered by Most Insurance Plans

including Medicare & Medicaid

We work directly with major insurance providers to verify coverage, submit claims, and assist with any required appeals — so you don’t have to worry about the paperwork.

Aetna Blue Cross Cigna Tricare United Healthcare John Hopkins Medicaid Medicare

How Esketamine (Spravato®) Can Help with Treatment Resistant Depression

Spravato® (esketamine) is an FDA-approved treatment for adults with treatment-resistant depression. It works differently from traditional antidepressants by targeting the brain’s glutamate system, which plays a role in mood regulation and neural communication.

For individuals living with Treatment-Resistant Depression who haven’t found relief from multiple antidepressants, Spravato® may offer a new option. By acting on different brain pathways, it may help reduce depressive symptoms when standard treatments haven’t been effective.

Spravato® treatment is personalized and guided by a comprehensive psychiatric evaluation. It is administered as a nasal spray in a certified clinical setting and must be used alongside an oral antidepressant, following FDA-approved protocols.

During each session, patients self-administer Spravato® under medical supervision and remain in the clinic for a monitored observation period. This allows the care team to ensure safety, comfort, and proper recovery after treatment.

Most patients return home the same day following observation. Treatment schedules and dosing are adjusted over time based on response and ongoing evaluation by the psychiatric provider.

What our patients say

What to Know About Esketamine(Spravato®) for Treatment Resistant Depression

Spravato® is an FDA-approved nasal spray used for adults with treatment-resistant depression. Unlike traditional antidepressants that mainly affect serotonin, Spravato® works on the brain’s glutamate system, which plays a role in mood and brain connectivity.

Because of this different mechanism, Spravato® may help people who haven’t improved after trying multiple antidepressant medications.

Spravato® may be an option for adults who have tried two or more antidepressants without adequate relief. Before starting treatment, you’ll meet with a psychiatric provider for a full evaluation to determine whether Spravato® is appropriate and safe for you.

Not everyone qualifies, and eligibility depends on medical history, current medications, and overall mental health needs.

During a session, you’ll self-administer Spravato® nasal spray in the clinic under medical supervision. After dosing, you’ll remain in a comfortable setting for a required observation period so the care team can monitor your response and ensure your safety.

You won’t be able to drive yourself home, so arranging transportation is required.

Spravato® follows a structured treatment schedule. Most patients start with twice-weekly sessions, then gradually move to weekly or less frequent maintenance visits, depending on response.

Your provider will regularly assess progress and adjust the schedule as needed to support long-term symptom management.

Yes, many major insurance plans cover Spravato® for eligible patients. Coverage varies by plan, and prior authorization is usually required.

Our team helps verify benefits, submit paperwork, and guide you through the approval process so there are no surprises.

Some patients experience temporary side effects such as dizziness, nausea, dissociation, fatigue, or changes in perception. These effects usually happen during or shortly after treatment and typically resolve the same day.

You’ll be monitored throughout your visit, and your provider will review potential risks and side effects with you before starting treatment.

Yes. Patients from Adelphi, MD and surrounding areas can receive Esketamine(Spravato) treatment at our North Bethesda clinic, conveniently located at 6000 Executive Blvd, Suite 101, North Bethesda, MD 20852. Our care coordinators help with scheduling, preparation, insurance verification, and follow-up care to make the process as smooth as possible.

If you’re unsure whether Spravato® is right for you, we can help arrange a consultation with a licensed mental health provider.

Rated 4.8 stars based on 171 reviews

Great doctor, very professional and friendly staff. They know how to make you feel comfortable, and actually feel good about talking of what is concerning you. Highly recommend this doctor and staff.
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Tony Latsio Avatar
Tony Latsio
06 Feb 2026
Salvaron mi vida!!! Tuve una depresión muy grande, con un dolor que no podía soportar. Estuve internada, visité dos psiquiatras me dieron diferentes medicamentos, pero nada funcionaba y mi vida era miserable, hasta que di con Bright Horizons. Desde el primer momento el doctor Etesam me dio el tratamiento y medicación adecuada y la Dra Valliath me hizo seguimiento continuo. La atención de todo el staff es increíble. Mil gracias por cambiar mi vida.
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Soledad Sosa Avatar
Soledad Sosa
31 Jan 2026
Dr Amir Etesam is a gem of a doctor. I was so nervous going into his office but he eased my mind with his knowledgeable expertise along with his kindness and detailed explanation of my options for treatment and who I need to see. He has excellent bedside manners and genuinely cares. He took his time answering my questions. Not rushing like so many others. For my particular case he gave me three references to call so I can set up an appointment to go see a neuropsychiatrist instead. He left open the fact that I can always go back to his office. I wish I could have been treated by him. I have been to many different doctors throughout my life. By far he is the best. I can't thank him enough for such a positive experience. His team is pleasant, friendly and making an appointment was easy. Very professional. The office is clean and the environment is light and positive.
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Beatriz De Leon Avatar
Beatriz De Leon
29 Jan 2026
As a psychotherapist myself, I’m very selective about where I refer my clients for medication management, psychological testing, and advanced treatments and Dr. Etesam and his team truly stand out as exceptional. Their practice offers an impressive and thoughtful range of services, from traditional psychiatry to TMS and ketamine treatments, all delivered with a level of care, professionalism, and integrity that is rare to find. I consistently feel confident referring my clients here because I trust the quality of care and the clinical expertise across the entire team. On a personal level, I am also a patient of Anita Paudel, and she has been absolutely wonderful! I always feel heard, supported, and well cared for. I highly recommend Dr. Etesam and his team to both colleagues and my own clients seeking high-quality, comprehensive psychiatric care.
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Olya Rich Avatar
Olya Rich
23 Jan 2026
Dr. V is very empathetic, understanding, and professional. I thank her immensely for the care that she gives. I would not have recovered and made it this far without her guidance and passion! By far the best experience I have had with a psychiatrist.
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Benjamin Lawrence Avatar
Benjamin Lawrence
31 Dec 2025
I feel like this may be a new beginning for me, the staff was very polite and helpful, the doctor was extremely helpful, made everything crystal clear, having some test done that I’ve never knew existed, so I’m finding new ways with these people to help me feel better about myself and get a new lease on life. Thanks to all Edward.
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Edward Bennett Avatar
Edward Bennett
18 Dec 2025
! This experience has had an extraordinary impact on my life. The staff are consistently accommodating and demonstrate exceptional empathy, which is especially meaningful in today
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leengi Edwards Avatar
leengi Edwards
11 Dec 2025
I had an excellent experience at this practice. The office is impeccably clean, comfortable, and has a calming, positive vibe. Everyone was professional and welcoming. The person I met with was on her A-game—confident, knowledgeable, and genuinely kind. She made me feel completely at ease even though I wasn’t sure what to expect. I left feeling impressed and grateful to have found such a competent and caring practice. 🫶
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Mella Davis Avatar
Mella Davis
04 Nov 2025
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Take the Next Step Toward Relief from Treatment Resistant Depression

If depression hasn’t improved despite trying multiple medications, Spravato® may be an option worth exploring. Our experienced care team is here to answer your questions, review your history, and help you understand whether this FDA-approved treatment is right for you.

Schedule a free consultation today to learn whether Esketamine (Spravato®) is right for you and get answers from a qualified care team.